Desensitization Therapy for Allergic Reactions to Antituberculous Drugs

Rapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series

Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...

Rapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series

Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...

Allergic reactions to drugs.

Systemic paradoxical response to antituberculous drugs: resolution with corticosteroid therapy.

the condition was self-limited. Cultures for streptococci were not performed for the partners, who were not described as having systemic complaints, in this study. Carlino and Calzavara [2] described a case of "chronic urethritis" with recurrent attacks of cellulitis. Chlamydiae were isolated at the onset, and group G streptococci were isolated each time the cellulitis recurred. No cultures wer...

AdDRESSing T-cell responses to antituberculous drugs

In this issue of the BJD, Ye et al.1 present data on T-cell-specific responses in patients with antituberculosis drug (ATD)-induced maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS). Understanding these responses helps further our knowledge of the immunopathogenesis of antituberculous hypersensitivity, and ideally it would be translated into diagnos...